Familial dyskeratotic comedones

Familial dyskeratotic comedones in a female with positive family history: A rare entity

Rodin et al. first reported a rare inherited condition in 1967, called as familial dyskeratotic comedones (FDC) with autosomal dominant mode of inheritance and clinically characterized by symmetrical development of cosmetically disfiguring, progressive but asymptomatic, numerous, discrete, disseminated, hyperkeratotic papules and comedones on trunk, arms and face, appearing around puberty [1]. ...

Perianal Comedones: A Rare Incidental Finding

Comedones occur when an overproliferation of keratinocytes blocks sebum secretion in a pilosebaceous duct. Comedones have multiple possible etiologies and contributing factors. While comedones are common to acne, they are also seen in occupational exposures and are associated with certain syndromes. We describe a particularly rare case of comedones at the perianus that is not associated with an...

Childhood flexural comedones: a new entity.

BACKGROUND Comedones are usually found in acne and involve the seborrheic areas of the skin. Disseminated comedones can be found in other skin disorders. Flexural comedones are characterized by double orifices connected by a thin layer of epidermis that reveals the comedo content below it. To the best of our knowledge, flexural comedones have not been previously described as an entity. Our obje...

Psoriasin and follicular hyperkeratinization in acne comedones.

pathological circumstances [5] . In the meantime, psoriasin has been suggested to be involved in the pathogenesis of inflammatory skin diseases, and its levels were found to increase in response to inflammatory stress. In addition, retinoic acid (RA) and inflammatory agents have been implicated in the upregulation of psoriasin [6, 7] . Psoriasin was shown to be induced not only in psoriatic epi...

Postherpetic Comedones in Two Chinese Han Patients